Endocrine Abstracts

Background: Literature suggests that whole glucose excursion, rather than plasma glucose concentration at a point, provides more information about glucose tolerance. The glucose area under the curve (AUC) is an index of whole glucose excursion after glucose load. We sought to investigate changes in insulin and glucose homeostasis, including the glucose AUC, 5 years after bariatric surgery.Method: A non-randomised prospective study of 18 participants with...

Background: Bariatric surgery aims to decrease cardiovascular risk factors. The Swedish Obese Subjects study reported that bariatric surgery was associated with reduction in long-term cardiovascular (CV) event. However, uncertainty remains regarding the effect of bariatric surgery on long-term CV risk. One way to predict long-term CV risk after bariatric surgery is to use cardiovascular risk assessment models.Aim: The aim of this study is to investigate ...

Background & Aims: ATP binding cassette subfamily G1 (ABCG1) is involved in mediating cholesterol efflux and modulating cellular lipid homeostasis. It is influenced by endogenous glucose and our aim was to examine the relationship between ABCG1 expression and lipid profiles within the increased glucose levels of subjects with Type 2 diabetes (ODM).Methods: RNA was extracted from visceral fat collected from subjects undergoing abdominal surgery (baria...